Re: JSLS. 2009;13(2):203-206 Laparoscopic Mucin Removal in Patients With Pseudomyxoma Peritonei
نویسندگان
چکیده
I write to you as a former patient of Pseudomyxoma Peritonei (PMP) and a member of many patient/research support organization for this disease and other peritoneal surface malignancies. The standard of care for PMP is cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). The efficacy and superiority of this treatment have been established by many studies across the world compared with serial debulking. The outcome of this treatment has shown survival rates of 85% in 20 year, according to the latest follow-up studies. At least 2 randomized trials and many multicentric studies support this claim. It has shown so much promise for PMP that it is now being extended to patients with peritoneal carcinomatosis from colon, gastric and ovarian cancer. The latest development in PMP is heading towards a more proactive and preventive outlook. It has been established that with this disease, minimally invasive procedures could only be justified for terminal cases.
منابع مشابه
Laparoscopic Mucin Removal in Patients with Pseudomyxoma Peritonei
BACKGROUND AND OBJECTIVES Pseudomyxoma peritonei results from ovarian and appendiceal mucinous tumors. Cyst rupture results in intraabdominal mucin accumulation, leading to abdominal distension. No effective treatment has yet been established. Pseudomyxoma peritonei is generally associated with a poor prognosis. In a recent Mayo Clinic report, the 5-year survival rate for this disease was 53% a...
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We accept the use of cytoreduction surgery and chemotherapy as initial therapy for PMP. For cases that have residual lesions and repeat recurrences, there is no useful treatment method that can significantly improve the prognosis. For patients who have a poor prognosis and repeat recurrences, repeat laparotomy is highly invasive. Thus, we performed laparoscopic mucin removal for patients with b...
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Background: Pseudomyxoma peritonei (PMP) is a rare disease with excess intraperitoneal mucin secretion. Treatment involves laparotomy, cytoreduction and chemotherapy that is very invasive with patients often acquiring numerous compromises. Hence a mucolytic comprising of bromelain and N-acetyl cystein has been developed to solubilise mucin in situ for removal by catherization. Owing to differen...
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Tumors of the appendix are rare entities causing mucoceles. The majority of them are discovered incidentally during investigation for other conditions. Laparoscopic surgery for appendiceal tumors is still controversial, as inadvertent rupture of the lesion due to improper handling will cause pseudomyxoma peritonei. The patient was incidentally discovered to have an appendiceal tumor and referre...
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Pseudomyxoma peritonei is a rare, chronic relapsing disease in which tumor cells in the abdomen produce excessive mucin with a significant mortality rate. We describe a young unmarried nulligrava who underwent fertility preservation by in vitro fertilisation and embryo cryopreservation prior to radical surgery and adjuvant chemotherapy. Pregnancy was achieved, although complicated by obstructiv...
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